Capabilities

Engine	Known bugs	4-site water models	5-site water models	Virtual sites on ligands	Proteins	Nucleic acids
All						No supported SMIRNOFF force fields
OpenMM	Link	Supported	Supported	Supported	Supported
GROMACS	Link	Partially supported	Supported	Partially supported	Supported
Amber	Link	Unsupported¹	Unsupported¹	Unsupported¹	Supported
LAMMPS	Link	Not supported	Not supported	Not supported	Not tested